L1 extraction — smart-immunizations

Everything an L1 extraction holds is a candidate: an agent decided it, and a person signs exclusions and reviews links. Counts here are what the files hold, not a reviewed result.

examples/l1-recommendation-scenarios/ (l1-recommendation-scenarios)

Not inside a library entry.

L1 statements (75)

75 recommendation

idtypestatementread fromfile
R01recommendationVaccination against measles is recommended for all susceptible children and adults.§position, p. 220measles/measles-position-paper-2017.l1.yaml
R02recommendationThe available live attenuated measles vaccines are safe and effective, provide long-lasting protection, are inexpensive and may be used interchangeably within immunization programmes.§position, p. 220measles/measles-position-paper-2017.l1.yaml
R03recommendationReaching all children with 2 doses of measles vaccine should be the standard for all national immunization programmes.§position, p. 220measles/measles-position-paper-2017.l1.yaml
R04recommendationCountries aiming at measles elimination should achieve ≥95% coverage with both doses equitably to all children in every district.§position, p. 220measles/measles-position-paper-2017.l1.yaml
R05recommendationIn addition to the first routine dose of MCV (MCV1), all countries should include a second routine dose of MCV (MCV2) in their national vaccination schedules regardless of the level of MCV1 coverage.§position, p. 220measles/measles-position-paper-2017.l1.yaml
R06recommendationAs the addition of routine MCV2 covers only a single birth cohort and it takes time to achieve high rates of population-wide coverage, countries conducting regular campaigns to achieve high population immunity should consider cessation of campaigns only when >90–95% vaccination coverage has been achieved at the national level for both MCV1 and MCV2, as determined by accurate coverage data for a p…§position, p. 221measles/measles-position-paper-2017.l1.yaml
R07recommendationIn countries with ongoing transmission in which the risk of measles mortality among infants remains high, MCV1 should be administered at 9 months of age.§timing, p. 221measles/measles-position-paper-2017.l1.yaml
R08recommendationThese countries should administer the routine dose of MCV2 at age 15–18 months.§timing, p. 221measles/measles-position-paper-2017.l1.yaml
R09recommendationThe minimum interval between MCV1 and MCV2 is 4 weeks.§timing, p. 221measles/measles-position-paper-2017.l1.yaml
R10recommendationIn countries with low levels of measles transmission (i.e. those nearing measles elimination or verified as having eliminated endemic measles virus transmission) and therefore the risk of measles virus infection among infants is low, MCV1 may be administered at 12 months of age to take advantage of the higher seroconversion rates achieved at this age.§timing, p. 221measles/measles-position-paper-2017.l1.yaml
R11recommendationIn countries where MCV1 is administered at 12 months of age, the optimal age for delivering routine MCV2 is based on programmatic considerations that achieve the highest coverage of MCV2 and, hence, the highest population immunity.§timing, p. 221measles/measles-position-paper-2017.l1.yaml
R12recommendationIf MCV1 coverage is high (>90%) and school enrolment is high (>95%), administration of routine MCV2 at school entry may prove an effective strategy for achieving high coverage and preventing outbreaks in schools.§timing, p. 221measles/measles-position-paper-2017.l1.yaml
R13recommendationIn the following situations, a supplementary dose of MCV should be given to infants from 6 months of age:§timing, p. 221measles/measles-position-paper-2017.l1.yaml
R13.1recommendationduring a measles outbreak as part of intensified service delivery;§timing, p. 221measles/measles-position-paper-2017.l1.yaml
R13.2recommendationduring campaigns in settings where the risk of measles among infants < 9 months of age remains high (e.g. in endemic countries experiencing regular outbreaks);§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R13.3recommendationfor internally displaced populations and refugees, and populations in conflict zones;§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R13.4recommendationfor individual infants at high risk of contracting measles (e.g. contacts of known measles cases or in settings with increased risk of exposure during outbreaks such as day-care facilities);§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R13.5recommendationfor infants travelling to countries experiencing measles outbreaks;§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R13.6recommendationfor infants known to be HIV-infected or exposed (i.e. born to an HIV-infected woman).§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R14recommendationMCV administered before 9 months of age should therefore be considered a supplementary dose and recorded on the child’s vaccination record as “MCV0” unless the country has data showing high seroconversion when vaccination is carried out before 9 months of age.§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R15recommendationChildren who receive a MCV0 dose should also receive MCV1 and MCV2 at the recommended ages according to the national schedule.§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R16recommendationCountries using MR or MMR in their national schedule should use the combined vaccine rather than measles-only formulations in all children, including those aged <1 year.§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R17recommendationBecause many cases of measles occur in children aged >12 months who have not been vaccinated, routine delivery of MCV1 should not be limited to infants aged 9–12 months and routine delivery of MCV2 should not be limited to infants aged 15–18 months of age.§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R18recommendationEvery opportunity (e.g. whenever children come in contact with health services) should be taken to vaccinate all children who missed one or both MCV routine doses, particularly those <15 years of age.§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R19recommendationPolicies prohibiting the use of the vaccine in children >1 year of age, older children and adolescents should be changed to allow them to be vaccinated as necessary.§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R20recommendationIrrespective of the strategy or schedule, the child’s immunization card and the clinic’s vaccination register should be designed to allow accurate recording of supplementary (MCV0), routine (MCV1 and MCV2) and campaign doses.§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R21recommendationChildren should be screened for their measles vaccination history at the time of school entry, and those lacking evidence of receipt of 2 doses should be vaccinated with any missing doses.§timing, p. 222measles/measles-position-paper-2017.l1.yaml
R22recommendationIn countries where health systems are functioning only moderately or weakly, implementation of regular measles vaccination campaigns can be a highly effective strategy for protecting children who do not have access to routine health services, particularly if hard-to-reach communities are targeted during the campaign.§campaigns, p. 222–223measles/measles-position-paper-2017.l1.yaml
R23recommendationBecause the risk of measles outbreaks is determined by the rate of accumulation of susceptible people in the population, programmes should use available good quality data on population immunity (i.e. vaccination coverage, surveillance, serological studies) to monitor the accumulation of susceptible people and conduct follow-up campaigns before the number of pre-school children susceptible to meas…§campaigns, p. 223measles/measles-position-paper-2017.l1.yaml
R24recommendationAs there is no single criterion for identification of the target age range for measles or measles/rubella vaccination campaigns, countries should integrate their surveillance, demographic, survey and seroprevalence data together with vaccination coverage information, history of MCV and RCV use, and local knowledge to determine the age distribution of susceptibility (age-specific immunity gaps) an…§campaigns, p. 223measles/measles-position-paper-2017.l1.yaml
R25recommendationAll MCV campaigns should follow established best practices, should be monitored to ensure readiness before the campaign, and be independently monitored during and after the campaign to ensure homogeneous vaccination coverage of >95%.§campaigns, p. 224measles/measles-position-paper-2017.l1.yaml
R26recommendationAll doses given during campaigns should be documented in the child’s vaccination record and the number of zero-dose children vaccinated (i.e. children who had not received any previous doses of MCV) recorded by age group.§campaigns, p. 224measles/measles-position-paper-2017.l1.yaml
R27recommendationBefore discontinuing campaigns, a review should be conducted by a national committee such as the national immunization advisory group.§campaigns, p. 224measles/measles-position-paper-2017.l1.yaml
R28recommendationIn the absence of adequate data, or if data suggest that cessation of campaigns would allow population immunity to drop below the herd immunity threshold, campaigns should continue.§campaigns, p. 224measles/measles-position-paper-2017.l1.yaml
R29recommendationAll commercially available live attenuated measles vaccines, either as monovalent vaccine or in combination with rubella, mumps, or varicella vaccines, or some combination of these, can be used interchangeably to protect against measles.§choice, p. 224measles/measles-position-paper-2017.l1.yaml
R30recommendationHowever, for programmatic reasons (e.g. to reduce cold storage needs and vaccine wastage), it is recommended that the same formulation is used for both routine doses of MCV.§choice, p. 224measles/measles-position-paper-2017.l1.yaml
R31recommendationAs a general rule, live vaccines should be given either simultaneously or at intervals of 4 weeks.§coadmin, p. 224measles/measles-position-paper-2017.l1.yaml
R32recommendationMCVs may be co-administered at different anatomical sites with other vaccines including Japanese encephalitis vaccine, yellow fever vaccine, DTP-containing vaccines, meningococcal vaccine, hepatitis B vaccine, inactivated poliovirus vaccine, Haemophilus influenza type b conjugate vaccine, and pneumococcal vaccines.§coadmin, p. 224measles/measles-position-paper-2017.l1.yaml
R33recommendationMCVs should not be given to individuals with a history of anaphylactic reactions or severe allergic reactions to any component of the vaccine (e.g. neomycin or gelatin) or those with any form of severe immunosuppression.§contra, p. 225measles/measles-position-paper-2017.l1.yaml
R34recommendationAs a precautionary measure, measles vaccine – alone or in combination with other vaccines – should be avoided during pregnancy.§pregnancy, p. 225measles/measles-position-paper-2017.l1.yaml
R35recommendationBecause of the known risk of spreading measles from HCWs to patients or from patients to HCWs, all HCWs and any staff who are in contact with patients should be immune to measles.§hcw, p. 225measles/measles-position-paper-2017.l1.yaml
R36recommendationVerification of vaccination and/or history of measles should be integrated into standard infection control guidelines or other standards of care for health-care workers.§hcw, p. 225measles/measles-position-paper-2017.l1.yaml
R37recommendationFor HCWs who have contact with patients, documentation of immunity should be required before signing an employment contract or entering into a training programme.§hcw, p. 225measles/measles-position-paper-2017.l1.yaml
R38recommendationVaccine should be offered to children from 6 months of age, adolescents and adults likely or known to be susceptible.§travel, p. 225measles/measles-position-paper-2017.l1.yaml
R39recommendationGiven the severe course of measles in patients with AIDS, measles vaccination should be routinely administered to potentially susceptible, asymptomatic HIV-infected children and adults.§hiv, p. 225measles/measles-position-paper-2017.l1.yaml
R40recommendationVaccination may even be considered for those with symptomatic HIV infection if they are not severely immunosuppressed according to conventional definitions.§hiv, p. 225measles/measles-position-paper-2017.l1.yaml
R41recommendationIn areas where there is a high incidence of both HIV infection and measles, an initial dose of MCV may be offered as early as age 6 months (recorded as MCV0). The 2 routine doses of MCV (MCV1 and MCV2) should then be administered to these children according to the national immunization schedule.§hiv, p. 225measles/measles-position-paper-2017.l1.yaml
R42recommendationAn additional dose of MCV should be administered to HIV-infected children receiving HAART following immune reconstitution.§hiv, p. 226measles/measles-position-paper-2017.l1.yaml
R43recommendationIf CD4+ T lymphocyte counts are monitored, an additional dose of MCV should be administered when immune reconstitution has been achieved, e.g. when the CD4+ T lymphocyte count reaches 20–25%.§hiv, p. 226measles/measles-position-paper-2017.l1.yaml
R44recommendationWhere CD4+ T lymphocyte monitoring is not available, children should receive an additional dose of MCV 6–12 months after initiation of HAART.§hiv, p. 226measles/measles-position-paper-2017.l1.yaml
R45recommendationA supplementary dose of MCV (recorded as MCV0) should be considered for infants known to be exposed (i.e. born to an HIV-infected woman) or soon after diagnosis of HIV infection in children older than 6 months who are not receiving HAART and for whom the risk of measles is high, with the aim of providing partial protection until they are revaccinated after immune reconstitution with HAART.§hiv, p. 226measles/measles-position-paper-2017.l1.yaml
R46recommendationAs countries approach elimination, they should intensify surveillance and move towards weekly reporting to the WHO regional offices.§surveillance, p. 226measles/measles-position-paper-2017.l1.yaml
R47recommendationTo limit the impact of measles outbreaks, WHO recommends surveillance for early detection, thorough assessment of the risk of spread and of severe disease outcomes, identification of immunity gaps, and planning rapid responses, including expanded use of MCVs.§surveillance, p. 226measles/measles-position-paper-2017.l1.yaml
R48recommendationA district or regional outbreak coordination committee with broad representation should make the decisions about the type of vaccination response to be implemented at the local level.§surveillance, p. 226measles/measles-position-paper-2017.l1.yaml
R49recommendationTo protect individuals at high risk during an outbreak, vaccination within 72 hours of exposure may be given to modify the clinical course of measles or prevent symptoms.§surveillance, p. 226measles/measles-position-paper-2017.l1.yaml
R50recommendationIn individuals for whom vaccination is contraindicated, the administration of measles immune globulin within 6 days of exposure may have a similarly beneficial effect.§surveillance, p. 226measles/measles-position-paper-2017.l1.yaml
R51recommendationWhen determining whether a country or the WHO Region as a whole has achieved elimination, the regional verification commission should consider 5 lines of evidence – disease epidemiology, population immunity, quality of surveillance, sustainability of the programme, and genotyping evidence – to allow for a comprehensive evidence-based assessment of past programme performance and future capacity to…§surveillance, p. 227measles/measles-position-paper-2017.l1.yaml
R52recommendationResearch targeting programmatic challenges is likely to yield the most programmatic gains and should be prioritized.§research, p. 227measles/measles-position-paper-2017.l1.yaml
V01recommendationIn general, it is recommended that freeze-dried vaccine be stored in a refrigerated condition below +8 °C.§vaccine-chars, p. 213measles/measles-position-paper-2017.l1.yaml
V02recommendationThe diluent must not be frozen and can be stored at ambient temperature; it should be cooled to 2–8 °C before reconstitution.§vaccine-chars, p. 213measles/measles-position-paper-2017.l1.yaml
V03recommendationThe vaccine is also sensitive to light and should be stored in coloured glass vials protected from sunlight.§vaccine-chars, p. 213measles/measles-position-paper-2017.l1.yaml
V04recommendationAfter reconstitution, the vaccine must be stored in the dark at 2–8 °C and used within 6 hours.§vaccine-chars, p. 213measles/measles-position-paper-2017.l1.yaml
V05recommendationMild, concurrent infections are not considered a contraindication to vaccination, but MCVs should be avoided if the patient has a high fever or other signs of serious acute illness.§safety, p. 217measles/measles-position-paper-2017.l1.yaml
C01recommendationSince measles is highly contagious, patient isolation is an important intervention to prevent further spread of the virus.§treatment, p. 210measles/measles-position-paper-2017.l1.yaml
C02recommendationSupportive care should be provided, including relieving common symptoms such as fever, cough, nasal congestion or rhinorrhea, conjunctivitis, and sore mouth.§treatment, p. 210measles/measles-position-paper-2017.l1.yaml
C03recommendationNutritional support is recommended to reduce the risk of malnutrition due to diarrhoea, vomiting and poor appetite associated with measles.§treatment, p. 210measles/measles-position-paper-2017.l1.yaml
C04recommendationBreastfeeding should be encouraged where appropriate.§treatment, p. 210measles/measles-position-paper-2017.l1.yaml
C05recommendationOral rehydration salts should be used as needed to prevent dehydration.§treatment, p. 210measles/measles-position-paper-2017.l1.yaml
C06recommendationAlthough one study reported that patients who received prophylactic antibiotics had fewer episodes of pneumonia and conjunctivitis and greater weight gain, antibiotics are generally not recommended for the treatment of measles unless secondary bacterial complications develop, such as pneumonia or otitis media.§treatment, p. 210measles/measles-position-paper-2017.l1.yaml
C07recommendationVitamin A should be administered to all acute cases irrespective of the timing of previous doses of vitamin A.§treatment, p. 210measles/measles-position-paper-2017.l1.yaml
C08recommendationVitamin A oral dosage should be given immediately on diagnosis and repeated the next day; 50 000 IU should be given to infants aged <6 months, 100 000 IU to infants aged 6–11 months and 200 000 IU to children aged ≥12 months.§treatment, p. 210measles/measles-position-paper-2017.l1.yaml
C09recommendationIf the child has clinical ophthalmic signs of vitamin A deficiency such as Bitot’s spots, a third dose should be given 4–6 weeks later.§treatment, p. 210measles/measles-position-paper-2017.l1.yaml
C10recommendationEven in countries where measles is not usually severe, vitamin A should be given in all cases of severe measles.§treatment, p. 210–211measles/measles-position-paper-2017.l1.yaml
C11recommendationIn unimmunized or insufficiently immunized individuals, measles vaccine may be administered within 72 hours of exposure to measles virus to protect against disease.§pep, p. 211measles/measles-position-paper-2017.l1.yaml
C12recommendationFor susceptible individuals for whom MCV is contraindicated, human immune globulin may be given after measles virus exposure, particularly to pregnant women, infants aged <6 months, and individuals with impaired immune systems.§pep, p. 211measles/measles-position-paper-2017.l1.yaml

Graph documents (1)

measles/candidates/scenario-candidates.l2.json

Context http://smart.who.int/kg/l2.context.jsonld; graph https://smart.who.int/immunizations/graph/l1-scenarios/immz-measles-wer9217.

node typenodes
user-scenario75
persona10
business-process4
edge predicateedges
involves78
implementedBy75
realises42

Files (6)

filewhat it isholdsbytesopen
README.mdMarkdown1,657source
measles/candidates/scenario-candidates.l2.jsonJSON-LD graph89 node(s), 195 edge(s)282,355source
measles/candidates/scenario-warnings.mdMarkdown9,687source
measles/immz-vocabulary.jsonl1-scenario-vocabulary/v18 persona(s), 9 process(es)8,808source
measles/measles-immz-mapping.yamll1-scenario-mapping/v175 mapped statement(s)48,559source
measles/measles-position-paper-2017.l1.yamlauthored L1 source75 recommendation(s) of Measles vaccines: WHO position paper – April 201749,640source

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